Dihydrocyclosporin D--a new immunosuppressive?
Estefan, M.; Beveridge, T.; Müller, W.
Zeitschrift für Rheumatologie 44(6): 275-277
1985
ISSN/ISBN: 0340-1855 PMID: 3913216 Document Number: 249374
The first preliminary clinical results with a new Cyclosporin derivative (Dihydrocyclosporin-D) are reported. The compound has no obvious nephrotoxic effect; but it exhibits a hepatotoxic effect, and frequently leads to hypertension. The clinical efficiency cannot yet be judged with certainty.