Penicillamine in ankylosing spondylitis: a double blind placebo controlled trial
Steven, M.M.; Morrison, M.; Sturrock, R.D.
Journal of Rheumatology 12(4): 735-737
1985
ISSN/ISBN: 0315-162X PMID: 3903158 Document Number: 249134
A double blind placebo controlled trial was carried out over a 6-month period on 17 patients with ankylosing spondylitis (AS) to assess the effect of the second line antirheumatic drug, D-penicillamine. The patients included 13 with peripheral joint involvement. No significant improvement over placebo was detected in a variety of clinical and laboratory indices in the patients receiving active treatment. This controlled trial would not support a use for penicillamine in AS.
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