Intraperitoneal cisplatin in peritoneal carcinomatosis patients
Toi, M.; Shiramizu, T.; Yonemura, T.; Ezaki, T.; Oka, N.; Yoshida, T.; Tsurumaru, H.
Gan no Rinsho. Japan Journal of Cancer Clinics 31(5): 522-526
1985
ISSN/ISBN: 0021-4949 PMID: 4040582 Document Number: 248736
Cisplatin (100 mg) was given by intraperitoneal infusion to 23 patients with peritoneal carcinomatosis. Eighteen patients had gastric cancer, and five had colorectal cancer. The effects of this therapy were as follows. 1) In gastric cancer patients, the mean survival period was 11.0 months. The cumulative survival rate was superior at the level of statistical significance in comparison with controls. 2) The side effects of this agent given intraperitoneally were mild. In particular, nausea was slightly less than with intravesicular or intraarterial infusion.
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