The antibacterial activity of gentamicin in the glucosuric environment
Papapetropoulou, M.; Giamarellou, H.
Drugs under Experimental and Clinical Research 11(11): 793-795
1985
ISSN/ISBN: 0378-6501 PMID: 3939216 Document Number: 248656
The antibacterial activity of gentamicin against 10 isolates of Escherichia coli and 10 of Pseudomonas aeruginosa was investigated in pooled human urine, with or without the addition of 20 g .permill. dextrose, and pH 6. Mean values for T50 under the influence of 50 mg/ml gentamicin were 3 .+-. 0.23 h vs 1.86 .+-. 0.10 h and 3.5 .+-. 0.08 h vs 1.56 .+-. 0.13 h with an osmolality of 1200 mosm/l and 820 mosm/l respectively.
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