AIDS epidemic at the beginning of the third millennium: time for a new AIDS vaccine strategy
Veljkovic, V.; Metlas, R.; Köhler, H.; Urnovitz, H.B.; Prljic, J.; Veljkovic, N.; Johnson, E.; Müller, S.
Vaccine 19(15-16): 1855-1862
2001
ISSN/ISBN: 0264-410X PMID: 11228354 DOI: 10.1016/s0264-410x(00)00194-8Document Number: 247921
Current expansion of AIDS pandemic significantly accelerates AIDS vaccine research resulting in development and clinical testing of several AIDS vaccine candidates. At the same time, available experimental and clinical data demonstrate that current AIDS vaccine strategy is unsuccessful resulting in development of inefficient and harmful vaccines. This overview briefly summarizes reported results which point out the requirement for moratorium on the current clinical trials of HIV-1 gp120/160 vaccines and urgent need for development of a new, efficient and safe AIDS vaccine strategy.