Cellular and regional localization of the neurospecific antigen 10-40-4 in the human brain
Kliushnik, T.P.; Kushner, S.G.; Aksenova, M.B.; Burbaeva, G.S.
Biulleten' Eksperimental'noi Biologii i Meditsiny 99(3): 296-298
1985
ISSN/ISBN: 0365-9615 PMID: 3886038 Document Number: 246161
Cellular and regional localization of neurospecific protein 10-40-4 in human brain was studied by immunofluorescent staining and immunoenzymatic assay. Intense fluorescence of perikaryons of the medulla oblongata, thalamus and pons neurons was demonstrated. The same structures showed the maximal concentration of the protein (15-18% of water-soluble proteins). In the cortex of the hemispheres, in the cerebellum and hypothalamus the fluorescence intensity was not different from the background level. The concentration of the protein in these structures was minimal (1-4% of water-soluble proteins).