Slipped capital femoral epiphysis: a pathological study. I. A light microscopic and histochemical study of 21 cases
Agamanolis, D.P.; Weiner, D.S.; Lloyd, J.K.
Journal of Pediatric Orthopedics 5(1): 40-46
1985
ISSN/ISBN: 0271-6798 PMID: 2579973 Document Number: 245976
Core biopsy specimens of slipped proximal femoral epiphyseal growth plates and of normal controls were examined by light microscopy and histochemistry. Slipped growth plates showed diminished cellularity with an overall excess of matrix as well as severe disorientation and misalignment of chondrocytes. Decrease in number of argyrophilic fibers in the longitudinal septa suggested deficiency in collagen. Histochemical staining of slipped plates did not deviate from normal except in severely deformed areas. Anatomic and histochemical observations did not conclusively support or exclude bio-chemical or biomechanical factors in the etiology of epiphyseal slipping.