Langerhans cells--their structure, function and pathological role
Persina, I.S.
Arkhiv Patologii 47(2): 86-93
1985
ISSN/ISBN: 0004-1955 PMID: 3888151 Document Number: 244152
Data on the structure and function of Langerhans' cells (LC) are presented. LC are defined as dendritic cells of the epidermis and mucous membrane epithelium having the mesenchymal origin and relating to the antigen-representing macrophages. Morphological, enzymatic and antigenic LC markers are characterized. The crucial role of LC in the development of the skin delayed type hypersensitivity is shown: contact hypersensitivity, specific inflammation, transplant rejection, neoplastic process.