Adolescent development in males with Down syndrome
Pueschel, S.M.; Orson, J.M.; Boylan, J.M.; Pezzullo, J.C.
American Journal of Diseases of Children 139(3): 236-238
1985
ISSN/ISBN: 0002-922X PMID: 3156491 Document Number: 243843
Growth features, development of primary and secondary sex characteristics, and pituitary and testicular hormone levels in 46 male adolescents and young adults with Down's syndrome were studied. Their mean height age was significantly less than and their mean bone age was slightly more than their chronological age. The subjects' secondary sex characteristics followed the same developmental pattern noted in youngsters without Down's syndrome. Penile length and circumference and testicular volume were not statistically different from those of normal adolescents. FSH, luteinizing hormone, and testosterone levels in the study population were similar to those reported for normal adolescents during sexual maturation.