A brief history of depot neuroleptics
Simpson, G.M.
Journal of Clinical Psychiatry 45(5 Part 2): 3-4
1984
ISSN/ISBN: 0160-6689 PMID: 6143745 Document Number: 241791
The development of phenothiazines used to treat psychotic states, and later of long-acting injectable forms, is discussed. Considerations affecting the clinical use of these drugs, including patient compliance and relapse, are reviewed briefly. The depot neuroleptics appear particularly useful for noncompliant, forgetful, and treatment-resistant patients.