Massive dobutamine overdose in a cardiovascular compromised patient
Goethals, M.; Demey, H.
Acta Cardiologica 39(5): 373-378
1984
ISSN/ISBN: 0001-5385 PMID: 6334955 Document Number: 241691
A case of dobutamine overdose is presented. Due to a prescription mistake a patient with recent myocardial necrosis and acute arterial occlusion received up to 70 mcg/kg/min of dobutamine IV. This resulted in arterial hypotension, diminished vascular resistance, oliguria and signs of cutaneous and mucosal hyperemia. Interruption of the dobutamine infusion and substitution with dopamine normalised all abnormalities. The differences between the hemodynamic profiles of dobutamine and dopamine are discussed.