Evaluation of lipid profile in adolescents during long-term use of combined oral hormonal contraceptives
Guazzelli, C.A.F.; Lindsey, P.C.; de Araújo, F.F.; Barbieri, M.ár.; Petta, C.A.; Aldrighi, J.M.
Contraception 71(2): 118-121
2005
ISSN/ISBN: 0010-7824 PMID: 15707561 DOI: 10.1016/j.contraception.2004.08.002Document Number: 240820
The study evaluated the effects of the long-term use of a combined oral hormonal contraceptive containing 30 microg ethinyl estradiol and 75 microg gestodene in adolescents. Thirty-three volunteers, aged from 14 to 19 years, who used the oral contraceptive for three consecutive years, were studied. Evaluation of total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides was made before use and after 1, 2 and 3 years. During the 3-year study period, total cholesterol, HDL-C, LDL-C and triglyceride levels were significantly higher than previous measurements, but average values did not exceed the normal range. Compared to the first year, the second- and third-year cholesterol, HDL-C, LDL-C and triglyceride levels were not significantly different.
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