Blood coagulation changes and pathogenesis of diabetic retinopathy. Recent advances
Porta, M.; Nuzzi, R.; Passera, P.
Minerva Medica 75(41): 2407-2420
1984
ISSN/ISBN: 0026-4806 PMID: 6390258 Document Number: 239972
In this review the most recent advances in blood coagulation and chronic complications of diabetes mellitus are discussed. Numerous research workers have reported abnormalities in the mechanisms of platelet activation, endothelial cell function, plasma coagulation and fibrinolysis. However, the data available today cannot as yet be interpreted in terms of pathogenesis of retinopathy or any other chronic manifestation of the disease. Consequently, there is at present no rationale for pharmacological prevention or treatment.