Immune deposits in the skin of patients with rheumatoid arthritis

McGill, P.E.; Brougham, P.A.; Tulloch, J.

Journal of Rheumatology 11(4): 454-456

1984


ISSN/ISBN: 0315-162X
PMID: 6384506
Document Number: 238418
The presence of immunoglobulin and complement deposits in cutaneous blood vessels and at the dermal junction was determined in 34 patients with rheumatoid arthritis (RA). Deposits of IgM and C3 were twice as common in the leg than the arm. The deposits were present in 7/14 patients with extraarticular disease and 1/20 patients with articular disease alone. Deposits of IgM were detected at the dermoepidermal junction in 4 patients with RA. All had circulating antinuclear antibodies.

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