Mental impairment in Parkinson's disease. the role of anticholinergic drugs
Meco, G.; Casacchia, M.; Lazzari, R.; Franzese, A.; Castellana, F.; Carta, A.; Iannuccelli, M.; Agnoli, A.
Acta Psychiatrica Belgica 84(4): 325-335
1984
ISSN/ISBN: 0300-8967 PMID: 6507124 Document Number: 237547
The trial has been carried out on 33 treated Parkinsonian patients and 14 healthy controls. A series of psychometric tests were employed in order to show a possible intellectual deterioration in Parkinsonian patients. Bender's test showed greater motor-perceptive deterioration in Parkinsonian patients respect to control, the Wechsler-Bellevue Intelligence Scale evidenced in patients significant deterioration of mnesic and psychomotor capacity. When considering drug treatments patients undergoing combined treatment or anti-cholinergics alone obtained worse results in all tests made whilst patients on L-Dopa alone obtained the best results.