Cushing's ulcer in childhood. Description of a case
Patanè, R.; Bottaro, G.; Ricca, O.; Iudica, M.L.; Nicosia, A.; Iudica, M.C.
La Pediatria Medica e Chirurgica Medical and Surgical Pediatrics 6(5): 719-723
1984
ISSN/ISBN: 0391-5387 PMID: 6535140 Document Number: 236984
The authors describe a case of Cushing's duodenal ulcer associated with Encephalitis. Diagnosis was made as the following criteria: neurological manifestations (fever, seizures, coma) and clinical manifestations of ulcer (hematemesis and melena); endoscopic evidence of ulcer and demonstration of increased gastric acid secretion; direct correlation between neurological lesion and duodenal ulcer. The good therapeutic result obtained with Ranitidine was noteworthy. The high dosage (20 mg/kg/die) allowed the control of the bleeding and the ulcer cicatrization.