The influence of the opiate antagonist naloxone on experimental pruritus

Fjellner, B.; Hägermark, O.

Acta Dermato-Venereologica 64(1): 73-75

1984


ISSN/ISBN: 0001-5555
PMID: 6203288
Document Number: 236646
The antipruritic effect of naloxone hydrochloride was evaluated in a double-blind, cross-over design. Systemic pretreatment with the opiate antagonist did not interfere with the cutaneous itch and flare responses evoked by morphine or histamine, nor did it inhibit the morphine-produced potentiation of the histamine-elicited skin reactions.

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