Risk factors and cumulative incidence of anaemia among human immunodeficiency virus-infected children in Uganda

Clark, T.D.; Mmiro, F.; Ndugwa, C.; Perry, R.T.; Jackson, J.B.; Melikian, G.; Semba, R.D.

Annals of Tropical Paediatrics 22(1): 11-17

2002


ISSN/ISBN: 0272-4936
PMID: 11926044
DOI: 10.1179/027249302125000102
Document Number: 235508
Anaemia has not been well characterised among HIV-infected children in sub-Saharan Africa. Baseline prevalence and cumulative incidence of anaemia (haemoglobin < 110 g/L) were 91.7% and 100% and, for moderate anaemia (haemoglobin < 90 g/L), were 35.1% and 58.4%, respectively, among 225 HIV-infected children followed from 9 to 36 months of age. Hospitalisation, suspected tuberculosis, malaria and height-for-age Z-score <-2 were significantly associated with moderate anaemia. Moderate anaemia and weight-for-height Z-score <-2 were associated with mortality. Anaemia is common and associated with increased mortality in HIV-infected children.

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