Determination of human apolipoproteins A-I, B, and E by laser nephelometry
Weisweiler, P.; Schwandt, P.
Journal of Clinical Chemistry and Clinical Biochemistry 22(1): 113-118
1984
ISSN/ISBN: 0340-076X PMID: 6421988 Document Number: 234194
A laser immunonephelometric procedure for the determination of human apolipoproteins A-I, B and E in serum and lipoproteins was developed. Coefficients of variation were 2.3-3.4% within-run, 4.7-4.9% between-run. Serum apolipoprotein A-I values were similar in normal and hyperlipoproteinemic subjects with a correlation coefficient of r = 0.585 to HDL -apolipoprotein B values less strongly (r = 0.472) correlated to the corresponding cholesterol levels. Serum apolipoprotein E concentrations were distinctly elevated in type III and not correlated to cholesterol values.