Waist-hip ratio and breast cancer risk in urbanized Nigerian women
Adebamowo, C.A.; Ogundiran, T.O.; Adenipekun, A.A.; Oyesegun, R.A.; Campbell, O.B.; Akang, E.E.; Rotimi, C.N.; Olopade, O.I.
Breast Cancer Research Bcr 5(2): R18-R24
2003
ISSN/ISBN: 1465-5411 PMID: 12631394 DOI: 10.1186/bcr567Document Number: 233769
The aim of this study was to examine the relationship between waist-hip ratio and the risk of breast cancer in an urban Nigerian population. Between March 1998 and August 2000, we conducted a case-control study of hospital-based breast cancer patients (n = 234) and population-based controls (n = 273) using nurse interviewers in urban Southwestern Nigeria. Multivariable logistic regression showed a significant association between the highest tertile of waist-hip ratio and the risk of breast cancer (odds ratio= 2.67, 95% confidence interval = 1.05-6.80) among postmenopausal women. No association was found in premenopausal women. The present study, the first in an indigenous African population, supports other studies that have shown a positive association between obesity and breast cancer risk among postmenopausal women.