Hypersensitivity to non-steroidal anti-inflammatory drugs--asthma precipitated by zomepirac. A case report
Botha, J.J.; Weich, D.J.
South African Medical Journal 65(5): 180-182
1984
ISSN/ISBN: 0256-9574 PMID: 6695277 Document Number: 233281
Non-steroidal anti-inflammatory agents can precipitate an asthma attack of varying severity. The most likely mechanism is the inhibition of the production of prostaglandin E with a concomitant increase in the production of the leukotrienes. A case in which an attack of asthma was precipitated by ingestion of 50 mg zomepirac (Zomax) and the patient responded to inhaled fenoterol is described. We conclude that zomepirac can cause reversible airflow limitation.