Systemic prophylaxis with gentamicin-metronidazole in appendicectomy and colorectal surgery: a prospective controlled clinical study
Gómez-Alonso, A.; Lozano, F.; Pérez, A.; Almazán, A.; Abdel-lah, A.; Cuadrado, F.
International Surgery 69(1): 17-20
1984
ISSN/ISBN: 0020-8868 PMID: 6735625 Document Number: 231794
A prospective, randomized, clinical study was carried out in 188 patients undergoing appendicectomy or colorectal surgery to test the efficacy of prophylactic, parenterally-administered antibiotics in the prevention of infection. The results show the effectiveness of the association gentamicin-metronidazole (9.4% of infections), compared to the control group with no antibiotics (39.1% of infections), X2 = 14.1; P less than 0.001).
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