Adjuvant chemotherapy in breast cancer: status in 1984
Jungi, W.F.
Wiener Klinische Wochenschrift 96(13): 486-492
1984
ISSN/ISBN: 0043-5325 PMID: 6382805 Document Number: 231206
Postoperative adjuvant chemotherapy prolongs the recurrence-free interval and, probably, overall survival in patients with surgically-treated, node-positive breast cancer. Composition, dosage, timing and duration of cytostatic treatment are not yet standardized. Among node-negative patients those with a relatively high risk of recurrence (receptor negative) should also be given adjuvant chemotherapy. Combination with endocrine treatment and/or radiotherapy merits further investigation. We need more large, well-designed controlled clinical studies to answer the numerous unsolved questions on this subject.