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Antibiotic resistance of gram negative rectal flora

Kanwar, A.; Mittal, S.K.; Ramachandran, V.G.; Varghese, A.

Indian Pediatrics 21(9): 729-735

1984

ISSN/ISBN: 0019-6061
PMID: 6519806
Document Number: 227753
Pattern of antibiotic resistance of Gram-negative bacteria isolated from rectal swab cultures of 381 diarrheal and 60 non-diarrheal children over a 2 yr period was studied in relation to various epidemiological factors. Escherichia coli were the most frequently isolated organisms being cultured from 257 (67.4%) of diarrheal and 35 (58.3%) of non-diarrheal cases. Strains (56) of Shigella were isolated from diarrheal cases and none from the non-diarrheal children. Only 1.6, 8.2 and 12.1% strains of E. coli were sensitive to ampicillin, streptomycin and chloramphenicol, respectively. Strains of Shigella (80.4, 80.4 and 94.6%) were resistant to chloramphenicol, streptomycin and ampicillin, respectively. Similar high prevalence of antibiotic resistance was seen in the isolated Klebsiella and Salmonella group of organisms. A pattern of antibiotic resistance was not affected by presence or absence of diarrhea. The antibiotic resistance pattern of 257 E. coli were studied in relation to various epidemiological factors, did not significantly affect the antibiotic resistance pattern of E. coli.

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