Thromboxane synthase inhibition combined with thromboxane receptor blockade: a step forward in antithrombotic strategy?
Gresele, P.; Van Houtte, E.; Arnout, J.; Deckmyn, H.; Vermylen, J.
Thrombosis and Haemostasis 52(3): 364
1984
ISSN/ISBN: 0340-6245 PMID: 6099616 Document Number: 227166
Document emailed within 1 workday
Related Documents
De Clerck, F.; Beetens, J.; de Chaffoy de Courcelles, D.; Vercammen, E.; Freyne, E.; Janssen, P.A. 1989: R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade, combined in one molecule Progress in Clinical and Biological Research 301: 567-572Golino, P.; Ambrosio, G.; Gresele, P.; Pascucci, I.; Ragni, M.; Russolillo, E.; Leproux, G.B.; Chiariello, M. 1993: The in vivo antiplatelet effects of thromboxane A2 synthase inhibitors are potentiated by simultaneous thromboxane A2/prostaglandin H2 receptor blockade Journal of Pharmacology and Experimental Therapeutics 266(2): 511-517
Hoet, B.; Arnout, J.; Vermylen, J. 1989: R68070, a combined thromboxane/endoperoxide receptor antagonist (TRA) and thromboxane synthase inhibitor (TSI), prolongs the bleeding time more than aspirin in man Progress in Clinical and Biological Research 301: 573-577
Welch, W.J.; Wilcox, C.S.; Dunbar, K.R. 1989: Modulation of renin by thromboxane: studies with thromboxane synthase inhibitor, receptor antagonists, and mimetic American Journal of Physiology 257(4 Pt 2): F554-F560
Nanji, A.A.; Rahemtulla, A.; Maio, L.; Khwaja, S.; Zhao, S.; Tahan, S.R.; Thomas, P. 1997: Alterations in thromboxane synthase and thromboxane A2 receptors in experimental alcoholic liver disease Journal of Pharmacology and Experimental Therapeutics 282(2): 1037-1043
Minoguchi, K.; Adachi, M. 2001: Thromboxane A2 synthase inhibitor and receptor antagonist Nihon Rinsho. Japanese Journal of Clinical Medicine 59(10): 1986-1991
Wilson, T.W.; Badahman, A.H.; Kaushal, R.D. 1993: Thromboxane synthase inhibition enhances furosemide-induced renal vasodilation Clinical and Investigative Medicine. Medecine Clinique et Experimentale 16(5): 372-378
Wisner, D.; Sturm, J.; Sutter, G.; Ellendorf, B.; Nerlich, M. 1988: Thromboxane receptor blockade in an animal model of ARDS Surgery 104(1): 91-97
Rossini, M.; Belloni, A.; Remuzzi, G.; Perico, N. 1990: Thromboxane receptor blockade attenuates the toxic effect of cyclosporine in experimental renal transplantation Circulation 81(1): I61
Nakayama, D.; Ikeda, T. 1988: Effect of OKY-046, a thromboxane synthetase inhibitor, on renal thromboxane synthesis in spontaneously hypertensive rat Nihon Jinzo Gakkai Shi 30(1): 79-84
Wilkes, B.M.; Hollander, A.M.; Sung, S.Y.; Mento, P.F. 1992: Cyclooxygenase inhibitors blunt thromboxane action in human placental arteries by blocking thromboxane receptors American Journal of Physiology 263(4 Pt 1): E718-E723
Chiabrando, C.; Broggini, M.; Castelli, M.G.; Cozzi, E.; Castagnoli, M.N.; Donelli, M.G.; Garattini, S.; Giavazzi, R.; Fanelli, R. 1987: Prostaglandin and thromboxane synthesis by M5076 ovarian reticulosarcoma during growth: effects of a thromboxane synthetase inhibitor Cancer Research 47(4): 988-991
Folger, W.H.; Lawson, D.; Wilcox, C.S.; Mehta, J.L. 1991: Response of rat thoracic aortic rings to thromboxane mimetic U-46,619: roles of endothelium-derived relaxing factor and thromboxane A2 release Journal of Pharmacology and Experimental Therapeutics 258(2): 669-675
Weber, C.; Beetens, J.R.; Tegtmeier, F.; Van Rooy, P.; Vercammen, E.; Wouters, L.; De Clerck, F. 1992: Ridogrel inhibits systemic and renal formation of thromboxane A2 and antagonizes platelet thromboxane A2/prostaglandin endoperoxide receptors upon chronic administration to man Thrombosis and Haemostasis 68(2): 214-220
Basevich, V.V.; Mevkh, A.T.; Varfolomeev, S.D. 1984: Kinetic mechanisms of enzyme activity of the thromboxane synthetase system. Thromboxane synthetase of human platelets Biokhimiia 49(9): 1538-1545
Mehta, J.; Mehta, P.; Lawson, D.L.; Ostrowski, N.; Brigmon, L. 1985: Influence of selective thromboxane synthetase blocker CGS-13080 on thromboxane and prostacyclin biosynthesis in whole blood: evidence for synthesis of prostacyclin by leukocytes from platelet-derived endoperoxides Journal of Laboratory and Clinical Medicine 106(3): 246-252
Ishiura, Y.; Fujimura, M.; Myou, S.; Amemiya, T.; Nobata, K.; Liu, Q.; Yamamori, C.; Matsuda, T. 2000: Effect of thromboxane synthase inhibitor, CS-518, on propranolol-induced bronchoconstriction in guinea pigs Drugs under Experimental and Clinical Research 26(2): 33-40
Sadilkova, L.; Paluch, Z.; Mottlova, J.; Bednar, F.; Alusik, S. 2012: The Purification Step is not Crucial in EIA Measurements of Thromboxane B 2 and 11-Dehydrothromboxane B2 in Human Plasma Clinical Laboratory 58(1-2): 177-183
Pieters, H.; Roodt, J.P.; Badenhorst, P.N.; van Wyk, V.; Schall, R.; Lötter, M.G.; Hundt, H.K.; Nel, C.J. 1993: Antithrombotic activity of Bay u3405, a thromboxane A2-antagonist, in patients with Dacron aortic grafts: a random controlled clinical trial Thrombosis and Haemostasis 70(6): 903-908
Welch, W.J.; Wilcox, C.S. 1990: Feedback responses during sequential inhibition of angiotensin and thromboxane American Journal of Physiology 258(3 Pt 2): F457-F466