The effect of a tar admixture to dithranol-salicylic-acid-white-petrolatum therapy on the cytokinetics of psoriasis
Schulze, H.J.; Steigleder, G.K.; Pullmann, H.; Bloedhorn, H.
Zeitschrift für Hautkrankheiten 59(5): 288-290; 295-297
1984
ISSN/ISBN: 0301-0481 PMID: 6719979 Document Number: 226405
The initial stimulation of DNA-synthesis after application of dithranol as single agent is completely inhibited by addition of tar. The autoradiographic analyse indicates that the good clinical effect of the new antipsoriatic therapy with TCSV may be due to suppression of dithranol-caused irritation by tar. But, restored cytokinetic values do not correspond to clinical remission of psoriasis.