Primary pulmonary emphysema associated with alpha-antitrypsin deficiency
Gembitskaia, T.E.
Klinicheskaia Meditsina 62(9): 86-91
1984
ISSN/ISBN: 0023-2149 PMID: 6333550 Document Number: 225132
The pathogenesis of primary pulmonary emphysema associated with .alpha.-antitrypsin deficiency is discussed. The content of .alpha.1-antitrypsin was determined in 137 patients with chronic non-specific lung diseases; primary lung emphysema was verified in 6 patients as a result of a combined clinical, functional and laboratory examination. Specific features of the clinical and X-ray picture of the disease were analyzed. .alpha.1-Antitrypsin deficiency contributes to the development of lung emphysema in subjects with chronic obstructive bronchitis-free history.