Sympathetic paraganglioma. Scintigraphic detection using a new labeled molecule, meta-iodobenzylguanidine
Baulieu, J.L.; Guilloteau, D.; Fetissof, F.; Caron, J.; Lecomte, P.; Guilmot, J.L.; Lipinski, F.; Baulieu, F.; Itti, R.; Pourcelot, L.
Presse Medicale 13(27): 1679-1682
1984
ISSN/ISBN: 0755-4982 PMID: 6234575 Document Number: 224223
Two cases of sympathetic paraganglioma are reported: one, benign, in a 20-years old woman with arterial hypertension and attacks of excessive sweating; the other, malignant and with bone metastases, in a 44-years old woman. Both were diagnosed by scintigraphy, using meta-iodobenzylguanidine as radionuclide. This new radiopharmaceutic agent has recently been introduced for the detection of phaeochromocytomas, but it seems to be a general tissue marker of catecholamine uptake and storage. Its use as a therapeutic compound may also be envisaged.