Liver and kidney damage in rifampicin and ethambutol treatment

Kozma, D.; Mihalik, P.

Zeitschrift für Erkrankungen der Atmungsorgane 162(3): 249-255

1984


ISSN/ISBN: 0303-657X
PMID: 6485386
Document Number: 223852
Case report on a 40 years old patient with pulmonary tuberculosis, in whom a treatment with Rifampicin plus Ethambutol has caused a transient hepatic and renal failure. By histology a chronic aggressive hepatitis and a destruction of renal tubular epithelium could be found. The etiologic role of Rifampicin is believed to be probable. Pathomechanism and differential diagnosis are discussed.

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