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Loxapine versus chlorpromazine in paranoid schizophrenia: a double-blind study

Tuason, V.B.; Escobar, J.I.; Garvey, M.; Schiele, B.

Journal of Clinical Psychiatry 45(4): 158-163

1984

ISSN/ISBN: 0160-6689
PMID: 6370967
Document Number: 223772
Newly admitted paranoid schizophrenic patients (N = 68) were treated with either loxapine or chlorpromazine for up to 4 weeks. Mean maximum dosages were 84 mg/day of loxapine and 820 mg/day of chlorpromazine. Loxapine showed efficacy superior to that of chlorpromazine, confirming earlier retrospective findings. Adverse reactions were also less troublesome with loxapine.

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