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An immunological investigation of catalase in three mammalian species

Klucis, E.; Masters, C.J.

Biochemistry International 8(4): 513-519

1984

ISSN/ISBN: 0158-5231
PMID: 6477617
Document Number: 221899
An immunological comparison of catalase has been conducted in the mouse, rat and guinea pig. In each of these species, enzyme activity from the peroxisomal compartment was indicated as immunologically distinct from the cytosolic activity, with catalase in the small granule compartment displaying intermediate characteristics. When related to the established data on the biogenetic and degradative changes of catalase in the mouse, the present results support the proposal that peroxisomal alterations, epigenetic modifications and degradative persistence are general characteristics of catalase biology in mammalian species.

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