Myxoid degeneration with prolapse and dystrophic calcification of the annulus fibrosus of the mitral valve. Pathological and clinical survey
Giampalmo, A.; Buffa, D.; Caponnetto, S.; Chiarella, F.; Pesce, C.; Sacchetti, R.
Applied Pathology 1(4): 194-208
1983
ISSN/ISBN: 0252-1172 PMID: 6678595 Document Number: 221066
Two degenerations of the mitral valve apparatus, namely myxoid degeneration of the mitral cusps and necrosis with subsequent calcification of the annulus fibrosus, are extensively reviewed and discussed. Both lesions are mainly noticed in elderly patients, with the possible exception of systemic dystrophies of the connective tissue associated with metabolic disorders. The clinicopathological correlations of several cases are reported, with special emphasis on modern diagnostic procedures and their wide anatomic spectrum.