Top Abstract Purchase Related
Home
>
Node
>
Subnode

Hexamethylenebisacetamide-mediated induction of murine erythroleukemia cells: relationship between expression of beta major and beta minor globin genes, globin mRNA synthesis and commitment to erythroid differentiation

Gambari, R.

Biochemistry International 7(4): 471-480

1983

ISSN/ISBN: 0158-5231
PMID: 6679742
Document Number: 220971
A switch in beta globin gene expression is operated in murine Friend erythroleukemia cells due to the inducing agent used. The competence of Friend cells to express beta major globin genes is operated within 8 hours exposure to hexamethylenebisacetamide. This early feature of induced differentiation is expressed in the absence of beta globin mRNA synthesis and is not suppressed by the corticosteroid hormone dexamethasone, which by contrast inhibits later stages of induced-mediated commitment to erythroid differentiation such as globin mRNA accumulation and heme synthesis.

Document emailed within 1 workday
Secure & encrypted payments

Carlson, D.P.; Ross, J.; Wierenga, P.K.; Nijhof, W. 1987: Expression of the 5'-flanking region of the beta major-globin gene in cultured murine erythroid precursor cells Experimental Hematology 15(8): 902-907
Bodine, D.M.; Karlsson, S.; Papayannopoulou, T.; Nienhuis, A.W. 1989: Expression of human beta globin genes introduced into primitive murine hematopoietic progenitor cells by retrovirus mediated gene transfer Progress in Clinical and Biological Research 316b: 219-233
Mulligan, R.C.; Howard, B.H.; Berg, P. 1979: Synthesis of rabbit beta-globin in cultured monkey kidney cells following infection with a SV40 beta-globin recombinant genome Nature 277(5692): 108-114
Mantei, N.; Boll, W.; Weissmann, C. 1979: Rabbit beta-globin mRNA production in mouse L cells transformed with cloned rabbit beta-globin chromosomal DNA Nature 281(5726): 40-46
Wright, S.; deBoer, E.; Grosveld, F.G.; Flavell, R.A. 1983: Regulated expression of the human beta-globin gene family in murine erythroleukaemia cells Nature 305(5932): 333-336
Ginder, G.D.; Burns, L.J.; Glauber, J.G.; Beck, J. 1989: Pharmacologic induction of embryonic globin gene expression in adult avian erythroid cells Progress in Clinical and Biological Research 316b: 327-339
Mamalaki, A.; Moschonas, N. 1989: Transcriptional regulatory factors may control the relative expression of human alpha 1 and alpha 2-globin genes in erythroleukemia cells Progress in Clinical and Biological Research 316a: 335-342
Paddock, G.V. 1989: Construction of mRNA genes for the synthesis and translation of duck alpha globin mRNA Biotechniques 7(8): 856-865
Thong, M.K.; Soo, T.L. 2005: The spectrum of beta-globin gene mutations in children with beta-thalassaemia major from Kota Kinabalu, Sabah, Malaysia Singapore Medical Journal 46(7): 340-343
Limborskaia, S.A.; Bukhman, V.L.; Prosniak, M.I.; Fedorov, A.N.; Slominskiĭ, P.A. 1987: Molecular causes of thalassemia. IV. Cloning of the beta-globin gene in a patient with beta-thalassemia from Azerbaijan and determination of the point mutation in a minor intron Genetika 23(2): 228-238
Kimura, T.; Mills, F.C.; Allan, J.; Gould, H. 1983: Selective unfolding of erythroid chromatin in the region of the active beta-globin gene Nature 306(5944): 709-712
Fordis, C.M.; Nelson, N.; Dean, A.; Schechter, A.N.; Anagnou, N.P.; Nienhuis, A.W.; McCormick, M.; Padmanabhan, R.; Howard, B.H. 1985: Trans-acting factors are responsible for the lack of beta-globin gene expression in K562 cells Progress in Clinical and Biological Research 191: 281-292
Zavodny, P.J.; Roginski, R.S.; Skoultchi, A.I. 1983: Regulated expression of human globin genes and flanking DNA in mouse erythroleukemia--human cell hybrids Progress in Clinical and Biological Research 134: 53-62
Forget, B.G.; Benz, E.J.; Spritz, R.A.; Weissman, S.M. 1982: Globin mRNA metabolism and gene structure in beta +-thalassemia Birth Defects Original Article Series 18(7): 51-59
Fucharoen, G.; Fucharoen, S.; Wilai, Y.; Chinoluck, P.; Khunsuk, S.; Sanchaisuriya, K.; Sae-ung, N. 1997: Beta-globin gene haplotypes in some minor ethnic groups in Thailand Southeast Asian Journal of Tropical Medicine and Public Health 28(Suppl 3): 115-119
Tuan, D.; Abeliovich, A.; Lee-Oldham, M.; Lee, D. 1987: Identification of regulatory elements of human beta-like globin genes Progress in Clinical and Biological Research 251: 211-220
Mathew, C.G.; Rousseau, J.; Berman, P.; Harley, E.H. 1983: Restriction endonuclease mapping of globin genes in beta-thalassaemia South African Medical Journal 64(11): 394-397
Perrine, S.P.; Miller, B.A.; Papayannopoulou, T.; Faller, D.V.; Rudolph, A.M.; Vichinsky, E.; Hurst, D.; Kan, Y.W. 1989: Butyrate analogues modulate globin gene expression in human and ovine erythroid cells Progress in Clinical and Biological Research 316b: 341-350
Myers, R.M.; Cowie, A.; Stuve, L.; Hartzog, G.; Gaensler, K. 1989: Genetic and biochemical analysis of the mouse beta-major globin promoter Progress in Clinical and Biological Research 316a: 117-127
Ginder, G.D.; Whitters, M.; Kelley, K.; Chase, R.A. 1983: In vivo demethylation of chicken embryonic beta-type globin genes with 5-azacytidine Progress in Clinical and Biological Research 134: 501-510