Nodal psammoma body in thyroid cancer as an indicator of cancer metastasis to the lymph node
Hosoya, T.; Sakamoto, A.; Kasai, N.; Sakurai, K.
Gan no Rinsho. Japan Journal of Cancer Clinics 29(11): 1336-1339
1983
ISSN/ISBN: 0021-4949 PMID: 6632214 Document Number: 220914
A 64-year-old woman underwent subtotal thyroidectomy and cervical lymphadenectomy for thyroid carcinoma. In 5 of 15 resected nodes, histologic examination revealed metastasis. The other 10 nodes showed no metastasis, though psammoma bodies were seen in 3 nodes. To clarify the relationship between psammoma bodies and metastasis, 10 cancer-negative nodes were serially sectioned (4 microns in thickness). This disclosed cancer cells and psammoma bodies in 2 to 3 psammoma body-positive nodes. We suggest that the presence of psammoma bodies in the lymph node may indicate metastasis.