Chondromyxoid fibroma. The experience at the Istituto Ortopedico Rizzoli
Gherlinzoni, F.; Rock, M.; Picci, P.
Journal of Bone and Joint Surgery. American Volume 65(2): 198-204
1983
ISSN/ISBN: 0021-9355 PMID: 6337162 Document Number: 220381
The records of all patients with the diagnosis of chondromyxoid fibroma were reviewed. The records of 27 patients were available for the study of clinical, radiographic and pathological findings. Surgical treatment was evaluated in 22 patients with a follow-up of > 2 yr, and their average follow-up was 117 mo. (range, 24-380 mo.). Patients (17) were followed for at least 4 yr. A questionnaire including a request for radiographs and questions pertaining directly to functional status was sent to the patients or their physicians. Seventeen (77%) of the patients responded and 2 other patients were examined. The remaining 3 patients had died due to unrelated causes, with no evidence of tumor at the time of death. The lesion was most commonly seen in the tibial metaphysis of adolesent boys. Symptoms of pain and swelling may precede detection of the lesion by years. Results are similar to those reported by other authors. There was an overall rate of recurrence of 27%. With curettage alone there was an 80% recurrence rate; when curettage was combined with corticocancellous bone-grafting, the recurrence rate decreased to 7%. Two of the recurrences had been treated by amputation in the mistaken belief that the lesion was malignant. The remaining recurrences were successfully treated by wide excision. The recurrence rate was not found to be dependent on the age of the patient or on an atypical histological appearance. Thorough curettage combined with corticocancellous bone-grafting remains the treatment of choice for patients with chondromyxoid fibroma.