Oncological characteristics of CC57BR mice

Iogannsen, M.G.; Vlasov, N.N.; Pliss, G.B.; Romanov, A.N.

Voprosy Onkologii 29(12): 72-78

1983


ISSN/ISBN: 0507-3758
PMID: 6666100
Document Number: 219220
The oncologic and non-oncologic morbidity in intact CC57BR mice was studied over a period of 1978-1980. Tumors occurred in 23.5%, while malignant tumors were in 14.3% of mice. Benign adenomas of lung were the most frequent 10.9%. Malignant tumors included generalized reticulosarcomatosis and leukemia 6.8%, cancer of the skin 3.4% and single different tumors. Pneumonia and enteritis were the most frequent among non-oncologic diseases. Since CC57BR mice belong to a low cancer line, they should be used for various long-term cancer and non-cancer experiments.

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