Major intolerance to carbamazepine. Acquired immunodepression or allergy?
Boissier, M.C.; Sansonetti, P.; Dupont, B.; Lapresle, C.
La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 59(43): 2989-2990
1983
ISSN/ISBN: 0037-1777 PMID: 6320381 Document Number: 216101
The authors report the case of an eight-year-old boy who developed erythroderma under carbamazepine. Other findings were enlarged lymph nodes, slight hepatic cytolysis, leuconeutropenia and decrease in the three classes of immunoglobulins. The immunosuppressive effect of the drug is recalled. Respective responsibility of immunosuppression and allergy is discussed.