Alpha-naphthyl butyrate esterase (a selective cytochemical monocyte marker)

Lippi, U.; Cappelletti, P.; Schinella, M.

La Ricerca in Clinica E in Laboratorio 13(4): 467-471

1983


ISSN/ISBN: 0390-5748
PMID: 6658305
Document Number: 216062
This paper describes a cytochemical technique for alpha-naphthyl butyrate esterase demonstration in monocytes obtained from peripheral blood of normal subjects, of a patient with reactive monocytosis and of a patient with myelomonocytic leukemia. It utilizes pH 6.1 alpha-naphthyl butyrate as substrate. At this pH value, alpha-naphthyl butyrate is a specific monocyte marker. The cytochemical procedure proposed is simple, rapid and standardized, as it utilizes stable and easily available reagents.

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