Malignant astrocytoma and glioblastoma. Therapeutic results
Rougier, A.; Pigneux, J.; Richaud, P.; Cohadon, F.
La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 59(7): 449-452
1983
ISSN/ISBN: 0037-1777 PMID: 6302883 Document Number: 216041
Statistical analysis of therapeutic results in malignant gliomas is impeded by the discrepancies between the various classifications. We have distinguished glioblastomas from malignant astrocytomas. The latter are defined as malignant gliomas other than glioblastomas with CT scan enhancement after IV contrast. The discrimination between these two types of tumor is justified by the very different actuarial survival curves. Total survival was not prolonged by chemotherapy in randomized studies. Systematic sequential treatment of glioblastomas with VM26-CCNU is questionable.