Abnormalities of T-cell subsets in Behçet's syndrome

Lim, S.D.; Haw, C.R.; Kim, N.I.; Fusaro, R.M.

Archives of Dermatology 119(4): 307-310

1983


ISSN/ISBN: 0003-987X
PMID: 6220679
Document Number: 215997
T cells and T-cell subsets were determined in the peripheral blood of 12 patients with Behcet's syndrome and 30 normal healthy control subjects. When compared with the control group, the mean percentage of T cells for the group with Behcet's syndrome was significantly decreased (73% vs. 61%). The mean percentage of T.mu. (helper) cells for the group with Behcet's syndrome (26%) was also significantly decreased from the mean value of the control group (42%). There was a concomitant significant increase of T.gamma. (suppressor) cells of the group with Behcet's syndrome (19%) over the mean value of the control group (10%). There were alterations of T cells and T-cell subsets in this disease.

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