Effect of ionophores a 23187 and valinomycin on acetyocholinesterase activity in rabbit erythrocytes
Reznik, L.V.
Voprosy Meditsinskoi Khimii 29(3): 77-79
1983
ISSN/ISBN: 0042-8809 PMID: 6410583 Document Number: 215957
Activity of cholinesterase was higher in young erythrocytes when the cell populations of various age were studied; the enzymatic activity was increased after addition of valinomycine into a medium independently on the antibiotic concentration and the enzyme activation was more pronounced in the old population of erythrocytes. The same alterations were observed in presence of calcium ionophore A 23187 and nystatin. Alterations in the enzymatic activity appear to depend on changes of erythrocyte membrane properties in ageing as well as on introduction of ionophore into the membrane.