Dialysis leucopenia--no correction after prolonged washing of the membrane
Hoenich, N.A.; Laing, C.; Buckley, P.; Woffindin, C.; Kerr, D.N.
International Journal of Artificial Organs 6(3): 113-114
1983
ISSN/ISBN: 0391-3988 PMID: 6874122 Document Number: 215665
Re-use of hemodialyzers diminishes the extent of leukopenia observed during hemodialysis. A possible cause of this change is the prolonged washing of the membrane by an aqueous solution on both sides and by protein contained solutions on the blood side which removes some substance from the membrane which affects leukocytes directly or by activation of complement. A series of studies to test this hypothesis were performed using 2 hemodialysis membranes.sbd.Cuprophan (Enka AG) and Cellulate (Cordis Dow Corporation).sbd.and the results obtained demonstrate no elution of any H2O soluble substance from the dialyzer membrane.