Salivary urea nitrogen as an index to renal function: a test-strip method

Akai, T.; Naka, K.; Yoshikawa, C.; Okuda, K.; Okamoto, T.; Yamagami, S.; Inoue, T.; Yamao, Y.; Yamada, S.

Clinical Chemistry 29(10): 1825-1827

1983


ISSN/ISBN: 0009-9147
PMID: 6616832
Document Number: 214518
To investigate the feasibility of using salivary urea nitrogen as an index of renal glomerular filtration rate, we developed and applied a new analytical system consisting of a urease-containing test strip and an automatic reflectance spectrometer. The concentrations of urea nitrogen so determined correlate well (r = 0.93) with concentrations in serum. These preliminary data suggest that our method can be used routinely as a simple and reliable means of detecting abnormalities of renal function.

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