Some aspects of contrast medium chemotoxicity
Dawson, P.
Acta Radiologica. Supplementum 366: 174-179
1983
ISSN/ISBN: 0365-5954 PMID: 6206688 Document Number: 214332
Intravascular contrast media exhibit a non-specific toxicity on account of their hyperosmolarity and a molecule specific toxicity which has been labelled 'chemotoxicity'. The new generation of low osmolar contrast media has achieved its purpose of greatly reducing the importance of the former and data are presented which demonstrate that all the new media also possess significantly lower chemotoxicity than their conventional predecessors. On most criteria iohexol has the lowest chemotoxicity of any of the available media.