Skin lesions related to a new anti-inflammatory agent: fenbufen. Apropos of 3 clinical cases
Nicolas, C.; Chouvet, B.; Cambazard, F.; Bernollin, C.; Thivolet, J.
Annales de Dermatologie et de Venereologie 110(5): 419-423
1983
ISSN/ISBN: 0151-9638 PMID: 6226230 Document Number: 213790
Three cases of generalized skin reactions occurred in patients undergoing oral therapy with Fenbufen (Cinopal), a new anti-inflammatory agent. The lesions spontaneously improved when the drug was discontinued. The role of Fenbufen in the pathogenesis of the lesions remains unclear. In the three cases, the detection of circulating immune complexes would suggest a sensibilization mechanism.