Portal obstruction in children. II. Results of surgical portosystemic shunts
Alvarez, F.; Bernard, O.; Brunelle, F.; Hadchouel, P.; Odièvre, M.; Alagille, D.
Journal of Pediatrics 103(5): 703-707
1983
ISSN/ISBN: 0022-3476 PMID: 6605420 Document Number: 213250
Children (76) with portal vein obstruction underwent surgical portosystemic shunt, for severe gastrointestinal tract bleeding in 64 and for prophylactic purposes in 12. Endoscopy and angiography or both showed shunt patency in 70 children; thrombosis occurred in the remaining 6. The mean age at successful shunt surgery was 6 yr 10 mo. Early postoperative assessment of shunt patency was judged from regression of splenomegaly and thrombocytopenia when splenectomy was not performed; when done, early postoperative ultrasonography correctly indicated the result. Significant regression of varices on endoscopy was most often delayed postoperatively for up to 6 mo. Children with a proved patent shunt did not have any further episodes of gastrointestinal tract bleeding, displayed no clinical signs of encephalopathy, and often exhibited a striking increase in growth velocity. These results strongly support the contention that a portosystemic shunt is the best treatment for portal vein obstruction after the 1st spontaneous bleeding episode, even in young children.