Postpartum hemorrhage: evidence-based medical interventions for prevention and treatment
Rajan, P.V.; Wing, D.A.
Clinical Obstetrics and Gynecology 53(1): 165-181
2010
ISSN/ISBN: 0009-9201 PMID: 20142654 DOI: 10.1097/grf.0b013e3181ce0965Document Number: 213084
Postpartum hemorrhage (PPH) remains a significant contributor to maternal morbidity and mortality throughout the world. The majority of research on this topic has focused on efforts to prevent PPH. Sound data exist that active management of the third stage of labor can reduce the occurrence of PPH. Although there remains debate regarding the optimal protocol for active management, it appears at this time that oxytocin is the preferable uterotonic to use. Misoprostol may be a reasonable option where parenteral administration of an uterotonic is not feasible. There is little evidence to guide treatment decisions should PPH occur.