Oncostatic properties of the complex of bivalent copper with 3-mercapto-2-hydroxypropyl ether of dextran (C-79)
Wieczorek, Z.; Giełdanowski, J.; Hraba, T.; Zimecki, M.; Mioduszewski, J.Z.
Archivum Immunologiae et Therapiae Experimentalis 31(5): 707-713
1983
ISSN/ISBN: 0004-069X PMID: 6202276 Document Number: 212483
The oncostatic properties of C-79 preparation were examined on the mice with: sarcoma Sa-180, melanoma B-16, Ehrlich carcinoma and leukemia P-388. The preparation was observed to prolong the life of animals with sarcoma Sa-180 and to modulate the morphology of tumors in them. The preparation had no effect on three remaining investigation models. The investigations carried out on mice of AKR strain have revealed that C-79 significantly suppresses the occurrence of spontaneous leukemia, prolonging the mouse survival-time.