Change in the renin-angiotensin-aldosterone system in the process of aging
Korkushko, O.V.; Asinova, M.I.
Problemy Endokrinologii 29(6): 33-37
1983
ISSN/ISBN: 0375-9660 PMID: 6657640 Document Number: 212202
The results of the studies performed indicate changes in homeostasis of the renin-angiotensin-aldosterone system in old people. A basal level of the blood renin activity and aldosterone concentration decreases, whereas the humoral mechanism sensitivity to regulatory actions of the sympathico-adrenal and hypothalamic-hypophyseal systems increases. The changes mentioned are associated with alterations of intrarenal hemodynamics and electrolyte balance in the organism.
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