The use of trimipramine in the treatment of peptic ulcer in Singapore
Kang, J.Y.; Ng, S.K.; Phay, K.L.
Singapore Medical Journal 24(6): 343-345
1983
ISSN/ISBN: 0037-5675 PMID: 6399628 Document Number: 212104
Patients (46) with peptic ulcer were treated with trimipramine in an open study. Ulcer healing was assessed by endoscopy. At 6 wk, 53% of gastric ulcer and 54% of duodenal ulcers had healed. All but 1 patient reported complete or partial relief of dyspepsia. Most patients developed drowsiness, but this was rarely severe. A controlled study to compare trimipramine against placebo or another agent of proven efficacy is required for formal evaluation of its ulcer healing properties.